啤酒花的黄酮类成分(4)
[8] Stevens J F，Ivancic M，Hsu V L，et al. Prenylflavonoids from Humulus lupulus[J]. Phytochem，1997，44(8)：1575.
[9] Tabata N，Ito M，Tomoda H，et al. Xanthohumols，diacylglycerol acyltransferase inhibitors，from Humulus lupulus [J]. Phytochem，1997，46(4)：683.
[10] Stevens J F，Taylor A W，Nickerson G B，et al. Prenylflavonoid variation in Humulus lupulus：distribution and taxonomic significance of xanthogalenol and 4′-O-methylxanthohumol[J]. Phytochem，2000，53(7)：759.
Flavonoids from Humulus lupulus
ZHANG Wei，ku1*， WANG Shou，bao2， FU Cheng，yu3， LI Ping1， XU Jie，kun4*
(1. Department of Pharmacology， Institute of Clinical Medical Sciences， China，Japan Friendship Hospital， Beijing 100029， China；
2. National Center for Pharmaceutical Screening， Institute of Materia Medica， Chinese Academy of Medical Sciences &
Peking Union Medical College， Beijing 100050， China；
3. Shaanxi Entry，Exit Inspection and Quarantine Bureau， Shaanxi Xi′an 710068， China；
4. School of Preclinical Medicine， Beijing University of Chinese Medicine， Beijing 100029， China)
[Abstract]Nine compounds were isolated and purified by column chromatographic techniques including macroporous resin， silica gel， ODS， Sephadex LH，20， and preparative reversed，phase HPLC. Their structures were elucidated as taxifolin (1)， naringenin (2)， chalconaringenin (3)， acacetin (4)， quercetin 3-O，β，D-galactopyranoside (5)， 6，prenylnaringenin (6) xanthohumol (7)， desmethylxanthohumol (8)， xanthohumol B (9) on the basis of MS and NMR spectroscopic data analysis. Compounds 1，5 were isolated from Humulus lupulus for the first time.
[Key words]Humulus lupulus； chemical constituents； flavonoid
doi：10.4268/cjcmm20131017, http://www.100md.com(张维库 王守宝 付骋宇 李平 续洁琨)
[9] Tabata N，Ito M，Tomoda H，et al. Xanthohumols，diacylglycerol acyltransferase inhibitors，from Humulus lupulus [J]. Phytochem，1997，46(4)：683.
[10] Stevens J F，Taylor A W，Nickerson G B，et al. Prenylflavonoid variation in Humulus lupulus：distribution and taxonomic significance of xanthogalenol and 4′-O-methylxanthohumol[J]. Phytochem，2000，53(7)：759.
Flavonoids from Humulus lupulus
ZHANG Wei，ku1*， WANG Shou，bao2， FU Cheng，yu3， LI Ping1， XU Jie，kun4*
(1. Department of Pharmacology， Institute of Clinical Medical Sciences， China，Japan Friendship Hospital， Beijing 100029， China；
2. National Center for Pharmaceutical Screening， Institute of Materia Medica， Chinese Academy of Medical Sciences &
Peking Union Medical College， Beijing 100050， China；
3. Shaanxi Entry，Exit Inspection and Quarantine Bureau， Shaanxi Xi′an 710068， China；
4. School of Preclinical Medicine， Beijing University of Chinese Medicine， Beijing 100029， China)
[Abstract]Nine compounds were isolated and purified by column chromatographic techniques including macroporous resin， silica gel， ODS， Sephadex LH，20， and preparative reversed，phase HPLC. Their structures were elucidated as taxifolin (1)， naringenin (2)， chalconaringenin (3)， acacetin (4)， quercetin 3-O，β，D-galactopyranoside (5)， 6，prenylnaringenin (6) xanthohumol (7)， desmethylxanthohumol (8)， xanthohumol B (9) on the basis of MS and NMR spectroscopic data analysis. Compounds 1，5 were isolated from Humulus lupulus for the first time.
[Key words]Humulus lupulus； chemical constituents； flavonoid
doi：10.4268/cjcmm20131017, http://www.100md.com(张维库 王守宝 付骋宇 李平 续洁琨)