[摘要]目的 探讨紫杉醇脂质体治疗晚期食管癌的效果。方法 选取我院2016年3月～2017年8月我院收治的晚期食管癌患者40例为研究对象，采用随机数字表法将其分为对照组(20例)、观察组(20例)。对照组采用常规治疗，观察组在此基础上联合紫杉醇脂质体治疗，比较两组的总有效率、不良反应发生率以及死亡率。结果 观察组的总有效率为85.00%，高于对照组的55.00%，差异有统计学意义(P<0.05);观察组患者的恶心呕吐、血红蛋白减少、肾功能异常、口腔黏膜异常、白细胞减少发生率均低于对照组，差异有統计学意义(P<0.05);观察组患者治疗后12个月的死亡率明显低于对照组，差异有统计学意义(P<0.05)。结论 紫杉醇脂质体治疗晚期食管癌的效果显著，安全性较高，具有临床应用价值。

    [关键词]紫杉醇脂质体;晚期食管癌;化疗;并发症

    [中图分类号] R735.1 [文献标识码] A [文章编号] 1674-4721(2019)10(b)-0072-03

    [Abstract] Objective To investigate the effect of Paclitaxel Liposome in the treatment of advanced esophageal cancer. Methods Forty patients with advanced esophageal cancer admitted to our hospital from March 2016 to August 2017 were selected as the research objects. The patients were divided into the control group (20 cases) and observation group (20 cases) using the random number table method. The control group was treated with routine treatment ......